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By S. H. Wright (auth.)

Advances in Comparative and Environmental Physiology presents finished, built-in stories giving sound, severe, and provocative summaries of our current wisdom in environmental and comparative body structure, from the molecular to the organismic point. the sector has now won the foreign prestige it merits and the association of a chain dedicated to it's very well timed in view of its genuine quick improvement. Biologists, physiologists, and biochemists, independently in their uncomplicated clinical orientation, will locate this new sequence of significant interest.

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Injection of cold or warm saline). 5 ml in all cases. The results were quite consistent for both series of experiments. To summarize, 13-lined ground squirrels entered hibernation quite readily in the summer after each and every of the above treatments; the rate of occurrence of hibernation ranged from 780/0 after sham injection to 86% each after warm saline, fresh summer active plasma, and fresh hibernating plasma, respectively. There was no difference in the time delay prior to onset of hibernation after each treatment; the average was as short as 3 days (range = 1 - 33) after cold saline to 18 days (range = 4 - 40) after warm saline with hibernating plasma averaging 5 - 7 days (range = 1 - 21) and summer active plasma 6 - 13 days (range = 1 - 34) after treatment.

1979). In the Columbian ground squirrel, the responsiveness of thermoregulatory responses to ICY morphine and Met-enkaphalinamide is reduced during the hibernating phase (Wang et al. 1987). This is consistent with the observed decrease in dihydromorphine binding to receptors in the cerebral cortex, septum, hippocampus, thalamus, and the amygdala during hibernation (Beckman 1986). Further, in the golden-mantled ground squirrel, physical dependence on morphine fails to develop during hibernation but develops in euthermia (Beckman et al.

Below 10°C, the increase in Smol of the nonhibernating preparation is greater than that of the hibernating preparation but the difference is small. Even at - 3 °C, about half of the membrane lipids from summer animals and more than half from hibernating animals remain in the liquid-crystalline state. 337, respectively, for summeractive and hibernating squirrels. 211, respectively, for the two states. None of these values are significantly different. Also, the Arrhenius plots of DPH fluorescence for both states are linear between 40 - 37 °C, indicating that no phase transitions occur in either summer or hibernating squirrels within this temperature range (Fig.

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